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FAQ
Purified Anti-Human CD45RO Monoclonal Antibody
| Product name: | Purified Anti-Human CD45RO Monoclonal Antibody | |
| Catalog: | DL21717F |
|
| Synonyms : | ||
| Reactivity: | Human | |
| Applications: | FCM | |
| Size: | 25 ??g/100 ??g | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines. |
|
| Concentration: | 0.2 mg/mL | |
| Buffer: | PBS with 0.05% Proclin300 | |
| Gene_ID: | 5788 | |
| Clone_NO: | UCHL1 | |
| SwissProt: | P08575 | |
| Isotype: | Mouse IgG2a, ? | |
| Storage: | Store at 2~8?? and protected from prolonged exposure to light. Do not freeze. | |
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